Antimicrobial Activity of Mycoflora Inhabiting Wastes
Poonam Agrwal, Rekha Shukla and A K Pandey
Rani Durgavati University, Jabalpur, MP, INDIA
Population, urbanization and industrialization generate waste making garbage pollution a serious problem to most cities. Waste provides an excellent site for colonization and multiplication of microorganisms including fungi.
Fungi are known to produce a wide range of secondary metabolites of high therapeutic values. We investigated on the antimicrobial potential of fungi inhabiting hospital, sewage and domestic waste
. Seventeen fungal
isolates were tested against Escherichia coli
. Curvularia lunata
which showed a maximum inhibitory activity, were further evaluated against eight pathogenic bacteria by disc diffusion method. Maximum inhibitory activity by C. lunata against Klebsiella pneumoniae
, Vibrio cholera
, E. coli and Enterococcus
sp. was detected in 20 days old fermented Richard’s broth. Antibacterial metabolite of C. lunata was observed to be thermo-labile.